CMT classification system

CMT classification uses numbers (1, 2, 3, 4, 6) to depict type and letters (A, B, C … ) to represent a subgroup within that type. An exception is type X (CMTX), which is passed down by X-linked inheritance.

The most common types are:

• CMT1: Demyelinating neuropathies (the protective layer around the nerve, known as the myelin sheath, is damaged, so the nerve signals transmit very slowly) Read more…
• CMT2: Axonal neuropathies (the axon is damaged, which leads to loss of the nerve signal) Read more…
• CMTX: X-linked gene inheritance
• CMT4: Recessive inheritance