CMT Research Foundation to Benefit From a Portion of Ticket Sales From Alan Jackson’s Last Call: One More For the Road – The “Finale”

The CMT Research Foundation is pleased to announce support from Alan Jackson’s Last Call: One More For the Road Tour – The “Finale” taking place Saturday, June 27, 2026 at Nissan Stadium in Nashville, Tennessee. Building on the success of Jackson’s 2022, 2024 and 2025 tours, the final show will continue to support and raise awareness for CMT by donating $1 from every ticket sold and will be bolstered by a generous CMTRF donor who will match Jackson’s Last Call Tour donation by $2.

The Finale: Saturday, June 27, 2026

Nissan Stadium – Nashville Tennessee

Jackson will be joined by Luke Bryan, Eric Church, Luke Combs, Riley Green, Cody Johnson, Miranda Lambert, Jon Pardi, Carrie Underwood, Keith Urban and Lee Ann Womack, with more multi-platinum, Grammy, CMA and ACM Award-winning artists to be announced!

Donate today to fund treatments for CMT, which would help Alan Jackson and all of the children and adults around the world battling this disease.

No treatments or cures currently exist for the millions of people living with CMT, but the science to change that does. Alan Jackson’s Last Call: One More for the Road Concert Tour is donating $1 for every ticket sold. The community is being challenged to match those donations. Your donation to the CMT Research Foundation today will support the most promising research that’s solely focused on drug development to deliver treatments during our lifetime.

 

What is CMT?

Charcot-Marie-Tooth disease, or CMT, is a progressive, degenerative disease involving the peripheral nerves that branch out from the brain and spinal cord to other parts of the body, including the arms, hands, legs and feet. CMT affects 150,000 people in the United States and nearly three million worldwide, and it is the most common inherited neuropathy, caused by over 140 known genetic mutations.

Typically, the brain and nerves are constantly communicating with each other. But with CMT, the motor nerves (the nerves that control our muscles) and sensory nerves (the nerves that carry sensory information like pain and temperature to the brain) don’t work properly. They have trouble sending signals to and from the brain. This results in numbness, sensory loss, muscle weakness/atrophy and nerve degeneration. Over time, the muscles weaken and deteriorate.

Symptoms may begin as early as birth or during adulthood, and they become gradually worse over time. There are currently no treatments or cures for CMT.

Does CMT affect children?

Yes, CMT can affect a child’s physical development and, in many cases, may require a child to wear leg braces and restrict their physical activities.  

Are there any approved treatments for CMT? 

There are no approved disease-modifying-therapies for CMT approved by the FDA. The CMT Research Foundation is leading on various drug development efforts to change this.   

How does CMTRF spend the money it raises?

CMTRF is focused on advancing and accelerating the development of treatments and cures for CMT. The CMT Research Foundation’s impact goes beyond simply making investments, we identify key challenges that are preventing the development of treatments, then aggressively find partners to address the challenges in order to accelerate drug development and encourage more scientists to work on CMT.

What is the overall state of research for CMT?

Even though there are currently no approved treatments for CMT, CMTRF believes we are getting close. Here are reasons for optimism in our search for a cure:

  • We understand the barriers to drug development for CMT
  • We are exploring many new forms of genetic medicines
  • We build upon learnings from other diseases to accelerate progress

What are some current CMTRF-funded research projects?

CMTRF has funded 32 research projects to date, six of which have drug candidates that are in active or preclinical trials.

Complete list here.

How can patients and families get involved in helping CMTRF? 

They can donate to CMTRF in a variety of ways, including recurring donations, annual gifts, and gifts from estates. They can also: 

    How can my business or organization support CMTRF’s mission?

    You can become a corporate sponsor of our organization and our annual Global Research Conference, fund research or cover our operating overhead that will free more resources directly for research. Additionally, you can lend your marketing expertise to help spread awareness of our mission.  You can also encourage your employees to give by matching all employee donations to the CMT Research Foundation.