Honoring Alan Jackson’s Career

Honoring a Legend. Funding a Cure. 

Alan Jackson has given a lot to country music over the course of his career, establishing a powerful artistic legacy. His Last Call: One More for the Road tour has highlighted just how much he’s contributed to the scene, bringing together superstars from every corner of country music. 

But this final tour has also raised money toward a cure for Charcot-Marie-Tooth (CMT) disease. 

When Alan revealed his own diagnosis with CMT, he used his platform to shine a light on a condition that affects nearly three million people worldwide. His final tour has raised both funds and awareness for CMT research, donating $1 from every ticket sold. 

Now, as Alan prepares for his final show on June 27, 2026 at Nissan Stadium in Nashville, we want to send him off the right way. 

35 #1 Hits. One Number to Remember. 

Over a career spanning more than three decades, Alan Jackson has claimed 35 number one hits across country music’s biggest charts. To honor that legacy and everything he has meant to this community, we’re asking fans to give in numbers that match his career: 

$35 | $350 | $3,500 

Every dollar goes directly toward funding the research that will cure CMT once and for all. The science exists. The momentum is real. What we need now is the resources to get us across the finish line. 

Give today in honor of an artist who has done so much for so many. When it’s all said and done, we’ll let Alan’s team know exactly how much was given in his honor. 

 

No approved treatments or cures currently exist for CMT, but the CMT Research Foundation is changing that. Your gift supports the most promising drug development research focused on delivering treatments within our lifetime. 

 

Frequently Asked Questions

What is CMT?

Charcot-Marie-Tooth disease, or CMT, is a progressive, degenerative disease involving the peripheral nerves that branch out from the brain and spinal cord to other parts of the body, including the arms, hands, legs and feet. CMT affects 150,000 people in the United States and nearly three million worldwide, and it is the most common inherited neuropathy, caused by over 140 known genetic mutations.

Typically, the brain and nerves are constantly communicating with each other. But with CMT, the motor nerves (the nerves that control our muscles) and sensory nerves (the nerves that carry sensory information like pain and temperature to the brain) don’t work properly. They have trouble sending signals to and from the brain. This results in numbness, sensory loss, muscle weakness/atrophy and nerve degeneration. Over time, the muscles weaken and deteriorate.

Symptoms may begin as early as birth or during adulthood, and they become gradually worse over time. There are currently no treatments or cures for CMT.

Does CMT affect children?

Yes, CMT can affect a child’s physical development and, in many cases, may require a child to wear leg braces and restrict their physical activities.  

Are there any approved treatments for CMT? 

There are no approved disease-modifying-therapies for CMT approved by the FDA. The CMT Research Foundation is leading on various drug development efforts to change this.   

How does CMTRF spend the money it raises?

CMTRF is focused on advancing and accelerating the development of treatments and cures for CMT. The CMT Research Foundation’s impact goes beyond simply making investments, we identify key challenges that are preventing the development of treatments, then aggressively find partners to address the challenges in order to accelerate drug development and encourage more scientists to work on CMT.

What is the overall state of research for CMT?

Even though there are currently no approved treatments for CMT, CMTRF believes we are getting close. Here are reasons for optimism in our search for a cure:

  • We understand the barriers to drug development for CMT
  • We are exploring many new forms of genetic medicines
  • We build upon learnings from other diseases to accelerate progress

What are some current CMTRF-funded research projects?

CMTRF has funded 32 research projects to date, six of which have drug candidates that are in active or preclinical trials.

Complete list here.

How can patients and families get involved in helping CMTRF? 

They can donate to CMTRF in a variety of ways, including recurring donations, annual gifts, and gifts from estates. They can also: 

    How can my business or organization support CMTRF’s mission?

    You can become a corporate sponsor of our organization and our annual Global Research Conference, fund research or cover our operating overhead that will free more resources directly for research. Additionally, you can lend your marketing expertise to help spread awareness of our mission.  You can also encourage your employees to give by matching all employee donations to the CMT Research Foundation.