News & Stories

See the latest news about CMT drug development and read stories from the CMT community that highlight why we must deliver treatments and cures during our lifetime.

The Inherited Neuropathy Consortium (INC) welcomes the CMT Research Foundation as a partner in their Patient Advocacy Groups

Jan 9, 2019 | CMT Research Updates, Press Releases

Today the Inherited Neuropathy Consortium (INC) named the CMT Research Foundation as a partner in their Patient Advocacy Groups. This gives the CMT Research Foundation access to INC resources, researchers and its clinical infrastructure through 21 CMT Centers of...

CMTRF Inks Milestone-Driven Partnership with AcuraStem to Repurpose Established Drugs for the Treatment of CMT

Dec 20, 2018 | CMTRF Funded Research, Press Releases

Focus will be on expansion of AcuraStem’s patient-based discovery platform, iNeuroRx™, to leverage patient neurons and advanced informatics technology to identify promising drugs ATLANTA (December 20, 2018) The newly launched CMT Research Foundation (CMTRF), a...

Is there a connection between CMT1X and Multiple Sclerosis?

Dec 18, 2018 | About CMT, CMT Research Updates

A recent study by Georgios Koutis et al at the National and Kapodistrian University of Athens recently published a paper in The Journal of Neurology, Neurosurgery and Psychiatry suggesting emerging evidence of a connection between CMTX1 and Multiple Sclerosis (MS)....

CMT Research Foundation Adds Dr. Charles Abrams and Jeff Ellman To The Team

Dec 18, 2018 | Press Releases

CMT Research Foundation (CMTRF), focused solely on delivering treatments and cures for Charcot-Marie-Tooth disease, added Jeff Ellman to its Board of Directors and Charles Abrams MD, Ph.D, to its Scientific Advisory Board. CMT is a progressive genetic nerve disease...

Two papers were recently published regarding CMT1B and Axonal Neuregulin 1 Type III (Nrg1TIII), a protein which builds myelin (the insulation) on the nerves.

Dec 14, 2018 | CMT Research Updates

In summary, there is a molecule which blocks the Nrg1TIII in CMT1B, causing the demyelination of the nerves. Both papers found that if the strength or amount of Nrg1TIII can be controlled, the nerves affected by CMT may be restored. When more of the protein is added...

Why FDA acceptance of gene therapy in SMA matters to CMT

Dec 7, 2018 | CMT Research Updates

Novartis's announcement about FDA filing acceptance could translate to CMT On Monday, Novartis, the parent company of AveXis, announced that a license application for their gene therapy approach to treat Spinal Muscle Atrophy (SMA) was accepted by the FDA. This is a...

Fontan Surgery for Heart Defects May Not Be Advisable for CMT1A Patients, Case Study Finds

Nov 19, 2018 | CMT Research Updates, Research News

Charcot-Marie-Tooth News reports the findings of a study where patients with Charcot-Marie-Tooth disease (CMT) who undergo Fontan surgery to correct a heart defect in childhood may later develop difficulties with the diaphragm — the muscle that allows us to breath —...

Where We Started, How Far We Have Come and Where We are Going

Nov 15, 2018 | Press Releases, Research News

The CMT Research Foundation offers hope to those living with CMT that a treatment and cure are on their way!

$1,000,000 pledge to CMT research

Nov 8, 2018 | Press Releases, Research News

CMTRF Receives $1 Million Research Grant from Grandview Steers Foundation The pace of research for CMT just got faster. Atlanta (November 8, 2018) The newly launched CMT Research Foundation (CMTRF), the only 501(c)(3) not-for-profit organization focused solely on...