2021 Year in Review
2021 has been a banner year for progress in CMT drug development, much of which has been possible because of your partnership with the CMT Research Foundation – thank you! Despite the challenges presented by a global pandemic, we can be proud of all that we were able...CEO Susan Ruediger featured on Global Genes podcast. LISTEN HERE
To read the full transcription click here.Discovery of a new gene found to cause CMT2
Two CMT Research Foundation Scientific Advisory Board members make a new discovery Congratulations to our Scientific Advisory Board members Drs. Charlotte Sumner and William Motley on their recent publication identifying a new gene implicated in CMT2. Genetic...Gene Therapy for Axonal Neuropathies
Gene Therapy for Axonal Neuropathies By Grace Pavlath, PhD I’ve written recently about gene therapy approaches in development for CMT1A, a form of CMT that affects the myelin sheath of nerves. There is also robust research to develop gene therapies for axonal forms...Are We Prepared for Clinical Trials in Charcot-Marie-Tooth?
A Review of Clinical Trial Readiness for CMT BY CMT RESEARCH FOUNDATION’S SCIENTIFIC ADVISORY BOARD MEMBER DR. ALEXANDER ROSSOR Read the full paper In this issue of Brain Research, Mike Shy, Mary Reilly and I summarize the current array of outcome measures for...
Important Research News Announcements
- The phenotypic spectrum of pathogenic ATP1A1 variants expands: the novel p.P600R substitution causes demyelinating Charcot-Marie-Tooth disease February 4, 2023
- Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules February 3, 2023
- Retraction: Charcot-Marie-Tooth Disease as a Risk Factor for Periprosthetic Fractures in Tibiotalocalcaneal Fusion With Intramedullary Nailing January 20, 2023
- INF2 mutations in patients with a broad phenotypic spectrum of Charcot-Marie-Tooth disease and focal segmental glomerulosclerosis January 13, 2023
- Exercise induced myelin protein zero improvement in neuropathic pain rats January 11, 2023
- A meta-analysis on the prevalence of Charcot-Marie-Tooth disease and related inherited peripheral neuropathies January 11, 2023
- X-linked Charcot-Marie-Tooth disease after SARS-CoV-2 vaccination mimicked stroke-like episodes: A case report January 11, 2023
- Targeting the PMP22 Protein to Develop Leads Against Charcot-Marie-Tooth Disease December 31, 2022
- Actin-mediated regulation of organelle dynamics in Charcot-Marie-Tooth disease December 31, 2022
- Electroceutical approach ameliorates intracellular PMP22 aggregation and promotes pro-myelinating pathways in a CMT1A in vitro model December 30, 2022